通过Oroxylum indicum药膏对动物感染细菌的抑制作用和对狗狗伤口的作用
Patchima Sithisarn1, Piyanuch Rojsanga2, Pakatip Ruenraroengsak3
1Department of Veterinary Public Health, Faculty of Veterinary Medicine, Kasetsart University, Kampangsaen Campus, Nakhon Pathom, Bangkok, Thailand.
Journal of advanced pharmaceutical technology & research
|September 18, 2024
概括
罗西印果实提取物膏显示抗菌和伤口愈合特性. 这种天然疗法在7-12天内有效地治愈狗狗的伤口,在动物模型中没有观察到急性毒性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品化学 自然产品化学
- 皮肤病学 皮肤病学
背景情况:
- 印花 (Oroxylum indicum) 是一种具有潜在药用功能的植物.
- 果实和O. indicum的种子提取物在体外表现出抗氧化和抗菌活性.
- 从自然来源开发局部抗菌剂具有显著的兴趣.
研究的目的:
- 使用O. indicum果实提取物制备局部抗菌药膏.
- 为了评估O. indicum药膏的抗菌疗效.
- 在动物模型中评估药膏的伤口愈合潜力和急性毒性.
主要方法:
- 使用O. indicum水果提取物制备局部膏,经过质量控制.
- 在动物模型中评估了提取物的急性毒性.
- 药膏的抗菌作用和伤口愈合能力在狗的伤口上进行了研究.
主要成果:
- 在O. indicum膏中,体外显示出对隔离细菌的抗菌活性.
- 在7天内,将药膏涂在狗的伤口上,导致了完整的上皮质化.
- 伤口大小在12天内减少了14%,在动物模型中没有观察到急性毒性.
结论:
- 在Oroxylum indicum膏中,它具有显著的体外抗菌活性.
- 药膏有效促进狗的伤口愈合,具有良好的安全性.
- O. indicum是开发局部抗微生物和伤口愈合剂的有希望的自然来源.
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