血清TSH水平与晚龄孕妇妊娠不良结果之间的关系
Xiufang Shao1, Kunhai Ren1, Haiyan Tang2
1Gynaecology and Obstetrics, Fujian Maternity and Child Health Hospital, Fuzhou 350000, China.
Journal of healthcare engineering
|September 18, 2024
概括
甲状腺刺激激素 (TSH) 水平显著影响老年母亲的怀孕结果. 异常的TSH水平,无论高低,都与不良结果和较低的婴儿分数有关,突出显示需要临床关注.
科学领域:
- 内分泌学 在内分泌学.
- 产科 产科 产科 产科 产科
- 围产儿医学 围产儿医学
背景情况:
- 先进的孕产妇年龄与不良妊娠结果的风险增加有关.
- 甲状腺功能障碍,通过血清甲状腺刺激激素 (TSH) 水平来表明,可能会影响怀孕健康.
研究的目的:
- 调查血清TSH水平与晚龄孕妇妊娠不良结果之间的相关性.
- 在不同TSH水平组中比较新生儿结局,包括出生体重和Apgar分数.
主要方法:
- 对97名老年分娩妇女的回顾性分析.
- 根据血清TSH水平分为三个组:低 (<0.25μIU/ml),高 (>4.00μIU/ml) 和正常 (0.25-4.00μIU/ml).
- 测量血清TSH,自由三甲状腺素 (FT3),自由甲状腺素 (FT4) 和免疫球蛋白 (IgA,IgG,IgM).
主要成果:
- 与正常TSH组相比,低TSH组 (20.00%) 和高TSH组 (17.14%) 的不良妊娠结果发生率显著更高 (2.38%).
- 从低或高TSH水平的母亲的新生儿中观察到较低的出生体重和Apgar分数.
- 与其他组相比,低TSH的组表现出更高的FT3,FT4,IgA,IgG和IgM水平.
结论:
- 血清TSH水平对晚期孕妇的妊娠结果起着至关重要的作用.
- 亚正常和超正常的TSH水平都与增加妊娠不良结果和新生儿健康状况较差的风险有关.
- 建议对老年孕妇的TSH水平进行密切监测,以改善临床管理.
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