脑卒中和COVID-19:一个总体审查
Kavous Shahsavarinia1, Nasim Hajipoor Kashgsaray2, Morteza Ghojazadeh1
1Research Center for Evidence-based Medicine, Iranian EBM Centre: AJBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Archives of academic emergency medicine
|September 18, 2024
概括
在COVID-19患者中,中风发生率为1.75%,主要是缺血性中风. 在这些中风患者中,超过32%的患者死亡,而许多患者康复良好或需要康复.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19已与急性脑血管疾病 (CVD) 相关,包括急性缺血性中风 (AIS) 和脑内出血 (ICH).
- 了解COVID-19患者中风的确切发生率和结果对于临床管理和公共卫生策略至关重要.
研究的目的:
- 系统地收集和分析有关COVID-19患者中风发病率,特征和结果的现有数据.
- 提供关于中风风险和与COVID-19相关的患者结果的全面概述.
主要方法:
- 一项对23项元分析的系统综述和元分析,包括795篇文章和5937名患者.
- 搜索了多个数据库 (PubMed,Scopus,知识网络,Embase,Cochrane) 并进行了手动搜索,参考检查和灰色文献审查.
- 使用AMSTAR检查清单评估报告质量,并使用Stata软件进行元分析.
主要成果:
- 在COVID-19患者中,中风的总发病率约为1.75% (缺血:1.59%,出血:0.3%).
- 受影响患者的平均年龄为62.3岁,68.3%为男性. 缺血性中风占病例的近80%.
- 死亡率为32.3%;27%的患者在轻度/没有并发症的情况下出院,28%的患者需要康复治疗.
结论:
- COVID-19与中风,特别是缺血性中风的显著发病率有关,在人口中平均年龄为62.3岁,男性占主导地位.
- 患有中风的COVID-19患者中有很大一部分面临中风死亡率 (32.3%),这凸显了这种并发症的严重性.
- 虽然很大一部分患者没有出现并发症或需要康复,但整体影响强调在COVID-19感染期间需要警管理脑血管风险.
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