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Updated: Jun 18, 2026

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一个自动化净化工作流程与材料节约高通量H NMR相结合,用于并行医药化学

Justin Bellenger1, Martin R M Koos1, Melissa Avery1

  • 1Medicine Design, Pfizer Inc., 445 Eastern Point Rd, Groton, Connecticut 06340, United States.

ACS medicinal chemistry letters
|September 18, 2024
PubMed
概括

一个新的自动化平台使得高通量净化和有机化合物的特征使用质谱和核磁共振光谱,即使在有限的材料.

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相关概念视频

Downstream Processing01:29

Downstream Processing

Downstream processing begins once fermentation is complete and involves a series of steps to recover and purify products such as acids, vitamins, antibiotics, or proteins.Cell HarvestingFor example, for intracellular protein-based products, the first step is harvesting the cells. This is typically achieved using centrifugation or filtration to separate the cells from the liquid phase.Cell Disruption for Intracellular ProductsIf the target product is intracellular, the harvested cells must be...