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Updated: Jun 12, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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含有氧气环和醇的呼吸道同胞性病毒聚合酶抑制剂的结构-活性关系

Minh T Tran1, Sandrine Grosse1, Rodrigo J Carbajo2

  • 1Janssen Pharmaceutica NV, 2340 Beerse, Belgium.

ACS medicinal chemistry letters
|September 18, 2024
PubMed
概括

通过修改JNJ-8003.3,开发出新的呼吸道同胞性病毒 (RSV) 聚合酶抑制剂. 这些新型化合物保持强大的抗病毒活性,为RSV感染提供潜在的新型暴露后治疗方法.

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