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良性设计的SAHA类似物用于人类和动物的媒介性寄生虫疾病

Michele Rossi1, Bianca Martinengo1, Eleonora Diamanti1

  • 1Department of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.

ACS medicinal chemistry letters
|September 18, 2024
PubMed
概括

研究人员使用绿色化学方法,从果仁的液体废物中开发出新型药物类似物. 化合物13对Trypanosoma brucei具有显著的活性,Trypanosoma brucei是一种导致非洲睡眠病的寄生虫,没有观察到毒性.

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