接受G-CSF的患者的大血管血管炎:未知起源发烧的可能差异
Raza Abbas Mahdi1, Venkata Subramanian Krishnaraju1, Bhagwant Rai Mittal1
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
概括
颗粒细胞殖民地刺激因子 (G-CSF) 治疗很少会导致大血管血管炎. 这一案例突显了G-CSF诱导的血管炎在肺癌患者,通过FDG-PET/CT成像识别.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 放射学 放射学是一门学科.
背景情况:
- 大血管血管炎是粒细胞殖民地刺激因子 (G-CSF) 治疗的罕见并发症.
- 颗粒细胞殖民地刺激因子 (G-CSF) 用于刺激白细胞的产生,通常在接受化疗的癌症患者中使用.
研究的目的:
- 在患有肺腺癌的患者中报告一个由粒细胞殖民地刺激因子 (G-CSF) 诱导的大血管血管炎的病例.
- 为了说明F-18流氧葡萄糖 (FDG) 定子发射断层扫描计算断层扫描 (PET/CT) 在诊断这种罕见的副作用的实用性.
主要方法:
- 一名患有肺腺癌的患者接受了新辅助化疗和基化G-CSF,发病了来源不明的发烧.
- 诊断评估包括F-18流氧葡萄糖 (FDG) 定子发射断层扫描计算断层扫描 (PET/CT).
主要成果:
- F-18流氧葡萄糖 (FDG) PET/CT揭示了化疗反应和大动脉中的新的,FDG-狂热的壁面加厚.
- 这些发现表明细粒细胞殖民地刺激因子 (G-CSF) 诱导的大血管血管炎.
结论:
- 颗粒细胞殖民地刺激因子 (G-CSF) 可以诱导大血管血管炎,即使是在癌症治疗的背景下.
- F-18流氧葡萄糖 (FDG) PET/CT是检测G-CSF诱导的血管炎的一个有价值的工具.
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