治疗长期意识障碍的针辅助疗法:一种随机,常规控制,评估者和统计学家盲目的试验的研究方案
Na Zhi1, Ning Sun2, Pan Huang1
1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Frontiers in neurology
|September 18, 2024
概括
这项研究调查了针治疗长期意识障碍 (pDOC) 的有效性. 研究人员的目标是为针作为pDOC患者的安全有效的补充疗法提供证据.
科学领域:
- 神经学 神经学
- 综合医学是一个整体医学.
- 临床试验 临床试验
背景情况:
- 长期意识障碍 (pDOC) 在神经康复中构成了重大挑战.
- 针作为pDOC的非药物补充疗法正在被探索.
- 目前对针治疗pDOC的有效性和安全性的强有力的证据有限.
研究的目的:
- 研究针辅助治疗对pDOC患者的疗效和安全性.
- 提供接受针治疗的pDOC患者意识水平的客观和主观评估.
主要方法:
- 一个单中心,前性,随机,受控试验,涉及110名参与者.
- 参与者被分配到针加常规治疗或仅接受常规治疗.
- 评估结果是使用昏迷恢复尺度修订 (CRS-R),四尺度,NCS-R,DRS和事件相关潜力 (ERP) 措施 (MMN,P300) 进行评估.
主要成果:
- 数据收集正在进行中,主要结果集中在CRS-R得分的变化上.
- 二次结果包括FOUR,NCS-R,DRS,MMN和P300的变化.
- 这项研究旨在提供有关针对意识的影响的全面数据.
结论:
- 这项试验旨在提供关于针治疗pDOC的临床有效性的可靠证据.
- 结果将指导临床决策和pDOC管理的未来研究.
- 该研究旨在通过结合临床量表和ERP技术来减少评估的主观性.
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