光学神经炎呈现为三角形自主头痛-三角形神经痛 (Tic) 重叠
Aubin Varghese1, Srilekha Durai2, P R Sowmini3
1Postgraduate Resident, Department of Neurology, Government Stanley Medical College and Hospital, Chennai, Tamil Nadu, India, Corresponding Author.
神经omyelitis optica光谱障碍 (NMOSD) 可以呈现出独特的面部疼痛,模仿三角神经疼痛和自主头痛. 早期诊断和治疗对于预防长期的神经损伤至关重要.
科学领域:
- 神经学 神经学
- 神经免疫学 神经免疫学
背景情况:
- 神经脊髓炎光学谱系障碍 (NMOSD) 是一种针对中枢神经系统的自身免疫性疾病.
- 面部疼痛,特别是三角形自主头痛 (TAC) 和三角形神经疼痛 (TN),是NMOSD的非典型但已知的神经症状.
- 延迟诊断NMOSD可能导致显著的发病率.
研究的目的:
- 要突出一个独特的NMOSD病例,呈现出严重的面部疼痛.
- 强调在非典型神经症状患者中考虑NMOSD的重要性.
- 讨论NMOSD的诊断挑战和管理.
主要方法:
- 病例报告详细介绍了一名32岁的女性患者,患有急性发性面部疼痛.
- 临床评估包括神经学检查和神经成像.
- 实验室调查,包括AQP4抗体测试.
- 用免疫抑制的治疗.
主要成果:
- 患者表现出V1-V2分布的面部疼痛,下神经功能障碍和长途症状.
- 两个先前的区域后热综合征 (APS) 发作最初被误诊.
- 诊断出AQP4血清阳性NMOSD,导致脑干症状恢复与免疫抑制.
- 后续包括疼痛的强力和神经病痛.
结论:
- 面部疼痛可能是NMOSD的呈现症状,涉及脊髓三角核.
- 区域后热综合征发作可能会先于其他NMOSD表现.
- 未经治疗的发作,AQP4阳性和早期复发是NMOSD长期发病的风险因素.
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