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Updated: Jun 29, 2026

Identifying Targets of Human microRNAs with the LightSwitch Luciferase Assay System using 3'UTR-reporter Constructs and a microRNA Mimic in Adherent Cells
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基于光素切换的侧流测定用于检测微RNAs

Ji Young Ryu1, Tae Su Choi2, Ki Tae Kim1

  • 1Department of Chemistry, Chungbuk National University, Cheongju 28644, Republic of Korea. ktkim@chungbuk.ac.kr.

Organic & biomolecular chemistry
|September 18, 2024
PubMed
概括

一种新的光素切换侧流测定 (LFA) 检测出前列腺癌的微RNA. 这种快速核酸测试 (NAT) 提供了敏感的肉眼检测,用于护理点诊断.

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相关概念视频

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...