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Updated: Jun 12, 2025

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
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肺动脉高血压和TGF-β超级家族信号传递:专注于Sotatercept

Benjamin Stump1, Aaron B Waxman2

  • 1Brigham and Women's Hospital, Boston, MA, USA.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy
|September 18, 2024
PubMed
概括

针对激素和TGF-β信号的新疗法在治疗肺动脉高血压 (PAH) 方面表现有前途. 索塔切和KER-012可以逆转疾病的血管损伤,解决一个关键的未满足的需求.

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