西班牙人口中中枢血压和血液动力学参数的进展以及与心血管风险因素的关系:EVA随访研究
David González-Falcón1, Leticia Gómez-Sánchez1,2, Marta Gómez-Sánchez1,3
1Department of Primary Care Research Unit of Salamanca (APISAL), Salamanca Primary Healthcare Management, Castilla y León Regional Health Authority (SACyL), Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
American journal of hypertension
|September 18, 2024
概括
中心血压 (CBP) 和脉压放大 (PPA) 在五年内增加,与体重指数和吸烟有关. 此外,CBP与周围血压的反相关性,因性别而异.
科学领域:
- 心血管生理学心血管生理学
- 高血压研究 高血压研究
- 流行病学 流行病学
背景情况:
- 中心血压 (CBP) 的进展及其与心血管风险因素的关联仍然不清楚.
- 了解这些血液动力学变化对于预防心血管疾病至关重要.
研究的目的:
- 在五年内调查CBP和中央血液动力学参数的进展.
- 确定这些血液动力学变化与西班牙成年人群中的心血管风险因素之间的关系.
主要方法:
- 一项前性观察性研究,对480名成年人进行了5年的随访.
- 通过使用SphygmoCor装置测量中心血压,遵循国际特别工作组的建议.
- 分析包括多重回归来评估与BMI和吸烟等危险因素的关联.
主要成果:
- 在随访期间,中央缩血压,中央透气血压和中央脉冲压都增加了.
- 中心缩血压和中心脉压的增加与体重指数 (BMI) 和吸烟有关.
- 脉压放大也增加,与BMI和吸烟有关.
结论:
- 大多数中央血液动力学测量,包括CBP和PPA,在五年内显示出进展.
- 人类测量参数 (BMI,腰部大小) 和吸烟与CBP和PPA进展有积极的关联.
- CBP的进展与周围血压的反向关联,并观察到性别特异性差异.
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