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在体内胎盘T2测量的单片和多片评估

Morteza Pishghadam¹, Julius S Ngwa¹, Yao Wu¹

¹Developing Brain Institute, Division of Diagnostic Imaging and Radiology, Children's National Hospital, Washington DC, USA.

|September 18, 2024

概括

单片胎盘T2评估提供了可靠的结果,可与全球措施相提并论,为评估怀孕期间胎盘健康提供了更有效的方法. 这支持临床使用的切片式方法.

科学领域:

医疗成像医学成像
产科和妇科产科和妇科
胎儿医学胎儿医学

背景情况:

胎盘健康对于母亲和胎儿的结果至关重要.
胎盘T2磁共振成像 (MRI) 可以在体内检测胎盘功能障碍.
对于胎盘T2评估的最佳感兴趣区域尚未确定.

研究的目的:

为了比较体内胎盘T2评估的全局和切片级测量.
为了确定切片智的胎盘T2评估是否与全球评估可比.

主要方法:

对单子妊娠的前性研究 (2017年12月 - 2022年2月).
获取3D多回声RF破坏的梯度回声序列.
使用全局和切片方法推导胎盘T2值;统计分析包括相关性和协议指标 (Pearson,CCC,ICC,Bland-Altman).

主要成果:

在整体队列或子组 (健康/高风险) 中,全球和切片评估之间的胎盘T2没有显著差异.
全球和切片式T2测量之间的高度一致性 (皮尔森,CCC,ICC:0.88-0.99).
布兰德-阿尔特曼分析显示T2差异在方法和组之间达成一致的95%范围内.

结论:

单片胎盘T2评估是强大的和可与全球评估相比较.
切片式方法可以减少后处理时间和SAR暴露.
切片式T2评估是评估不同怀孕中胎盘健康的有效替代方案.

关键词:

磁共振成像技术磁共振成像技术胎盘胎盘胎盘胎盘怀孕怀孕怀孕怀孕 T2 影像成像技术

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