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Updated: Jun 12, 2025

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脂化部位对α-螺旋型抗菌的活性的影响

Marta Makowska1, Anna Wardowska2, Marta Bauer3

  • 1Department of Organic Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.

Bioorganic chemistry
|September 18, 2024
PubMed
概括

抗微生物 (AMP) 在氨酸侧链上的脂质修饰,而不是N端,增强了对格拉姆阴性细菌的活性,并降低了毒性. 这一战略为开发新型脂质-联体提供了一个有前途的途径.

关键词:
抗微生物是一种抗微生物.脂肪酸是一种脂肪酸.脂是一种脂.体膜相互作用的作用.自动组装自动组装结构活动关系结构活动关系

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