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Updated: Jun 12, 2025

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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一个全性环林E-CDK2位点,通过对比跳跃与共价探头绘制地图

Yuanjin Zhang1, Zhonglin Liu1, Marscha Hirschi2

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.

Nature chemical biology
|September 18, 2024
PubMed
概括

化学蛋白质组学揭示了与氨酸残留的共价相互作用如何在蛋白质对应物中识别药物标. 这种方法可以发现新的抑制剂,用于以前未被准的蛋白质,如CCNE1:CDK2.

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M cyclin...
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