2023年ACR/EULAR抗脂综合征分类标准确定患有并发症高风险的患者
Diana Castillo-Martínez1, Mauricio Mora-Ramírez2, Raúl Molina-Sánchez2
1Dermatology, Hospital General de Zona 32, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Clinical rheumatology
|September 18, 2024
概括
2023年ACR/EULAR标准有效地识别了抗脂综合征 (APS) 患有并发症高风险的患者,与调整后的全球抗脂综合征评分 (aGAPSS) 相对应良好. 这有助于风险分层,以便更好地管理患者.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 临床医学 临床医学
背景情况:
- 识别患有主要抗脂综合征 (APS) 并发症高风险的患者对于有效管理至关重要.
- 现有的分类标准可能无法完全捕捉所有初级APS患者的风险概况.
研究的目的:
- 评估2023年美国风湿病学院/欧洲反风湿病联盟 (ACR/EULAR) 对抗脂综合征 (APS) 的分类标准的实用性.
- 评估2023年ACR/EULAR标准的能力,以识别使用调整的全球抗脂综合征评分 (aGAPSS) 患有并发症高风险的初级APS患者.
主要方法:
- 一个单中心研究,使用修订的札标准和2023年ACR/EULAR标准对初级APS患者进行分类.
- 用调整的全球抗脂综合征评分 (aGAPSS) 来评估并发症风险.
主要成果:
- 2023年ACR/EULAR标准确定了很大一部分患者 (36/45) 也符合札标准.
- 符合2023年ACR/EULAR标准的患者的aGAPSS得分明显更高,表明并发症风险更高 (p=0.005).
- 在两组标准之间观察到一个显著的一致性 (91%),2023年ACR/EULAR标准与aGAPSS.S.的实验室领域的相关性更强.
结论:
- 2023年ACR/EULAR分类标准有效地识别了患有并发症风险增加的初级APS患者.
- 这些标准与aGAPSS相关,特别是其实验室组件,有助于风险分层.
- 这些发现支持2023年ACR/EULAR标准在临床实践中用于管理APS患者的实用性.
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