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关节关节疾病的关节切开术:随机对照试验的网络元分析

Jun-Ming Zhang¹, Jie Yun², Tian-Qi Zhou³

¹School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

BMC oral health

|September 18, 2024

概括

氨酸加上富含血小板血 (HA+PRP),可注射的富含血小板纤维素 (i-PRF) 和骨髓缩物 (BMAC) 在不同时间点对关节疾病 (TMD) 有效. 这些治疗方法为TMD症状和关节功能恢复提供了最佳的管理.

科学领域:

整形外科整形外科整形外科
再生医学是一种再生医学.
口腔和牙面部外科手术

背景情况:

关节切除术对关节关节疾病 (TMD) 有效.
关于TMD关节缩的最佳注射药物存在缺乏共识.
越来越多的药物正在接受TMD治疗的研究.

研究的目的:

进行随机对照试验 (RCT) 的网络元分析.
为了比较各种关节切开治疗方案对TMDs的临床疗效.
为了确定TMD管理的最佳注射剂.

主要方法:

在2024年7月29日之前,对Embase,PubMed,Cochrane图书馆和Web of Science进行全面的文献搜索.
使用 Stata 17.0.0 进行的网络元分析.
使用视觉模拟尺度 (VAS) 评分和最大无助打开变化来评估有效性,用于排名的是积累性排名曲线 (SUCRA) 下面的表面.

主要成果:

包括40个涉及1904个关节 (TMJs) 的RCT.
研究中的药物包括富含血小板的血 (PRP),氨酸 (HA),皮质类固醇 (CS),骨髓缩物 (BMAC),可注射的富含血小板的纤维素 (i-PRF),缩生长因子 (CGF),Tenoxicam (TX) 和微分片脂肪组织 (FAT).
关节节切除术后1个,3个和6个月的最佳治疗方法分别是HA+PRP,i-PRF和BMAC.

结论:

氨酸加上富血小板血 (HA+PRP) 显示出短期TMD管理的前景.
可注射的富血小板纤维素 (i-PRF) 是有效的中期缓解症状和功能恢复.
骨髓缩剂 (BMAC) 是一种最佳的药物,可用于长期治疗TMD.

关键词:

关节动脉造术 (英语:Arthrocentesis) 是一种关节动脉造术.生物产品是生物产品.网络元分析网络元分析部关节部关节短关节疾病短关节疾病

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