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Updated: Jun 12, 2025

Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells
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Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells

Published on: December 3, 2015

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通过PROTAC介导的维门丁降解促进了多能干细胞的末端红色球分化

Hao Yan1, Ruge Zang2, Tiantian Cui1

  • 1Beijing Institute of Radiation Medicine, Beijing, 100850, P. R. China.

Stem cell research & therapy
|September 18, 2024
PubMed
概括

人类多能干细胞衍生的红色素细胞中维门 (VIM) 的保留会损害核化. 使用PROTAC平台降解维门丁,通过增强核极化,加速红状腺核化.

关键词:
培养的红细胞细胞.核除菌是指核除菌的方法.红色素质的形成Erythropoiesis这就是PROTAC.两极化的偏化在Vimentin中,使用了Vimentin.

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