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在雅瓦岛的雅加达 (Yogyakarta) 中ABO和D抗原表达的分布:印度尼西亚的一项开创性的大规模研究
Hasna Fadlilatul Bidayah1, Teguh Triyono2,3, Yann Fichou4,5
1Biotechnology Study Program, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia.
BMC research notes
|September 18, 2024
概括
印度尼西亚献血者中最常见的血液型是O,其次是B,A和AB. D阳性血液明显比D阴性更为普遍,与全球模式保持一致.
科学领域:
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
- 人口遗传学 人口遗传学
背景情况:
- 了解血型分布对于输血服务和公共卫生至关重要.
- 关于印尼ABO和D抗原频率的先前数据有限,特别是来自大规模研究的数据.
研究的目的:
- 为了确定ABO和D血型表型在印度尼西亚的Yogyakarta的献血者中的分布.
- 为优化国家输血指南提供基础数据.
主要方法:
- 对献血者注册数据的回顾性分析.
- 从2018年1月到2023年12月收集的ABO和D抗原的表型数据.
- 对捐赠人群的表型频率的计算.
主要成果:
- 总共分析了245,307名捐赠者.
- ABO表型的频率:O (38.5%) > B (29.4%) > A (24.1%) > AB (8.0%). 在这些表型中,
- D阳性表型的频率为99.5%,而D负的频率为0.5%.
结论:
- 这项研究是关于印尼献血者ABO和D表型分布的首份大规模报告.
- 观察到的频率与全球和东南亚的模式一致.
- 这些发现支持在国家一级协调优化输血指南.
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