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相关概念视频

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

919
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
919
Tumor Immunotherapy01:27

Tumor Immunotherapy

491
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
491
Humoral Immune Responses01:36

Humoral Immune Responses

72.2K
Overview
72.2K
Development of Immunocompetence01:22

Development of Immunocompetence

294
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
294
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF01:24

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

119
Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
119
Immunological Memory01:23

Immunological Memory

557
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
557

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相关实验视频

Updated: Jun 12, 2025

Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation
10:35

Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation

Published on: December 26, 2017

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针对免疫缺陷的免疫球蛋白治疗.

Bridget E Wilson, Catherine M Freeman

    Allergy and asthma proceedings
    |September 19, 2024
    PubMed
    概括

    免疫球蛋白替代疗法 (IRT) 通过静脉或皮下途径提供被动免疫. 这一审查涵盖了IRT.

    科学领域:

    • 免疫学和医学 免疫学和医学

    背景情况:

    • 免疫球蛋白替代疗法 (IRT) 为抗体缺乏提供了被动免疫力.
    • 可用的途径包括静脉注射 (IVIG) 和皮下注射 (SCIG).
    • 路线选择影响剂量,频率,益处和风险.

    研究的目的:

    • 提供免疫球蛋白替代疗法的全面概述.
    • 讨论特定路线的管理,不良影响和管理策略.
    • 对IRT患者的监测和疫苗接种指南进行审查.

    主要方法:

    • 文献综述和关于免疫球蛋白治疗的当前知识的综合.
    • 讨论选择路线和产品的临床考虑.
    • 对不良影响,风险因素和缓解策略的分析.

    主要成果:

    • IVIG和SCIG在剂量,频率和施用方便方面有所不同.
    • 患者的并发症会影响最佳的免疫球蛋白产品选择.
    • 通过适当的风险评估和监测,可以控制不良影响.

    结论:

    • 服用途径和产品成分是IRT的关键因素.
    • 了解和管理不良影响对于患者安全至关重要.

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  • 标准化的监测和疫苗接种方案可以提高治疗结果.