相关实验视频

Updated: Jun 12, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

肺在免疫的先天性错误中的肺

Sonia Restrepo-Gualteros^1,2, Gustavo Nino^3,4, Maria J Gutierrez⁵

¹School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia.

Pediatric pulmonology

|September 19, 2024

概括

天生的免疫错误 (IEI) 经常导致影响各种肺结构的肺部疾病. 诊断需要综合的临床,成像和分子方法来有效管理.

科学领域:

免疫学免疫学免疫学
肺部病理学肺部病理学
医学遗传学医学遗传学

背景情况:

肺在免疫防御中起着至关重要的作用.
免疫的先天性错误 (IEI) 常见于影响呼吸道,气泡,间歇体,血管和肺部的肺部疾病.

研究的目的:

概述患有天生的免疫错误的患者肺部并发症的诊断和管理策略.
强调多学科方法在应对这些复杂条件时的重要性.

主要方法:

临床病史和体检.
高分辨率计算机断层扫描 (HRCT) 用于成像图案.
肺功能检测,支气管镜检查与支气管膜洗,以及肺活检进行呼吸评估.
分子诊断包括临床表型,功能性免疫研究和遗传检测.

主要成果:

通过HRCT准确识别肺部疾病模式,以指导进一步的评估.
分子诊断对于识别免疫缺陷和指导向治疗至关重要.
由于IEI的复杂性,需要采用多学科的方法.

结论:

结合临床,成像和分子数据的综合诊断方法对于管理IEI肺部并发症至关重要.
需要进行持续的研究,以改善IEI肺部表现的治疗方法和患者的治疗结果.

关键词:

支气管切除症是一种支气管切除.免疫调节失调免疫调节失调免疫的先天错误免疫的先天错误间歇性肺病间歇性肺病肺部感染肺部感染原发性免疫缺陷是一种主要的免疫缺陷

更多相关视频

Flow Cytometric Analysis for Identification of the Innate and Adaptive Immune Cells of Murine Lung

Flow Cytometric Analysis for Identification of the Innate and Adaptive Immune Cells of Murine Lung

Published on: November 16, 2021

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease

Published on: April 12, 2021

相关概念视频

Gross Anatomy of the Lungs

Gross Anatomy of the Lungs

The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...

Pulmonary Cycle: Exhalation

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

Pleura of the Lungs

Pleura of the Lungs

The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Anatomy of Respiratory System II: Lower Respiratory Tract

Anatomy of Respiratory System II: Lower Respiratory Tract

The lower respiratory tract is anatomically composed of several vital structures, including the larynx, trachea, bronchial tree, alveoli, lungs, and pleurae. Each component has a specific function, and all are intricately connected to ensure efficient respiration.
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...