Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers01:12

Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers

924
Class III antiarrhythmic drugs are a group of medications that can prolong action potentials in the heart. They achieve this by blocking potassium channels or enhancing inward currents from sodium channels. However, these drugs have a unique property of "reverse use-dependence," which is most pronounced at slower heart rates and can lead to torsades de pointes—a specific type of arrhythmia. However, it is essential to note that excessive QT interval prolongation—a measure of...
924
Depolarizing Blockers: Mechanism of Action01:28

Depolarizing Blockers: Mechanism of Action

1.5K
Depolarizing blockers act on skeletal muscle fibers' membranes and induce their depolarization. Most depolarizing blockers have two quaternary N+ atoms that bind the nicotinic acetylcholine receptors and cause neuromuscular blockade within minutes.
Succinylcholine is the most commonly used depolarizing blocker. Chemically, it constitutes two molecules of acetylcholine joined together by an acetate methyl group. They act on the receptors in the same way as acetylcholine. Because...
1.5K
Cardiac Action Potential01:30

Cardiac Action Potential

1.1K
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
1.1K
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers01:20

Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers

791
Class IV antiarrhythmic drugs, such as verapamil and diltiazem, block calcium channels. They primarily affect the heart, slowing the conduction in calcium-dependent tissues like the SA and AV nodes. These drugs manage reentrant supraventricular tachycardia (SVT) and reduce ventricular rate in atrial flutter/fibrillation.
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
791
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers01:24

Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers

718
Adrenergic stimulation generally impacts cardiac rate and rhythm. Specifically, stimulation of the β-adrenoceptors triggers an increase in intracellular calcium ion influx and pacemaker currents, which may cause arrhythmias. Catecholamines like adrenaline also demonstrate β2-adrenoceptor-mediated hypokalemia, impacting cardiac action potential and disrupting the normal cardiac rhythm. Class II antiarrhythmic drugs are β-adrenoceptor antagonists or β-blockers, which...
718
Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

916
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
916

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Demographic and Geographic Disparities in Atrial Fibrillation and Cirrhosis Mortality in the United States: A Twenty-Five-Year Analysis From 1999 to 2023.

Cardiology research·2026
Same author

Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, and Somatic (VEXAS) Syndrome: A Case Report.

Cureus·2025
Same author

Herpes Simplex Esophagitis in an Immunocompetent Adult.

Cureus·2025
Same author

Uncommon Streptococcus Constellatus Meningitis Leading to Pulmonary Abscess and Brainstem Infarct in an Immunocompetent Patient.

The American journal of case reports·2024
Same author

Cocaine-Induced Toxic Leukoencephalopathy: A Case Report.

Cureus·2024
Same author

Munchausen Syndrome.

Southern medical journal·2020
Same journal

Managing Rheumatic Mitral Stenosis Complicated by Shock and Cardiac Cirrhosis Beyond Guidelines.

JACC. Case reports·2026
Same journal

Transfemoral TAVR in Chronic Type A Aortic Dissection and Severe Aortic Stenosis.

JACC. Case reports·2026
Same journal

Papillary Endothelial Hyperplasia Mimicking Right Atrial Infective Thrombus: Percutaneous Aspiration and Diagnosis.

JACC. Case reports·2026
Same journal

Inclisiran Response in a Patient With Familial Hypercholesterolemia After Suboptimal Response to Evolocumab.

JACC. Case reports·2026
Same journal

Dual-Level Left Ventricular Outflow Tract Obstruction in an Adult.

JACC. Case reports·2026
Same journal

Combining Renal Autotransplantation and Endovascular Aortic Repair for Abdominal Aortic Aneurysm in an LVAD Patient.

JACC. Case reports·2026
查看所有相关文章

相关实验视频

Updated: Jun 12, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.6K

胺终止持久性心室动脉短心

Rejina Fahhoum1, Bilal Abaid1, Zachary Ellis1

  • 1Baptist Memorial Hospital North Mississippi, Oxford, Mississippi, USA.

JACC. Case reports
|September 19, 2024
PubMed
概括
此摘要是机器生成的。

静脉动脉冲动 (VT) 风暴是一种严重的心律问题,可以耐标准治疗. 这项案例研究表明,氨酸成功地终止了患者的静脉风,为患者提供了新的治疗选择.

科学领域:

  • 心脏病学 心脏病学
  • 药理学 药理学是指药理学的学科.
  • 关键护理医学 关键护理医学

背景情况:

  • 腹腔动脉短拍 (VT) 是一种严重的心律失常,与心脏突然死亡有关.
  • 风暴的特点是经常出现风暴,需要迅速和积极的抗节律干预.
  • 耐火静脉风暴通常需要先进的治疗方法,如镇静,机械通风或导管切除.
关键词:
抗心律失常药物 抗心律失常药物胺基氨酸是什么 胺基氨酸耐火性心室性心跳动.腹腔动脉冲动脉风暴是什么意思

更多相关视频

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
07:56

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts

Published on: February 17, 2023

889
Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
05:12

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

3.1K

相关实验视频

Last Updated: Jun 12, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.6K
A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
07:56

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts

Published on: February 17, 2023

889
Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
05:12

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

3.1K