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Updated: Jun 12, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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肝脏Dyrk1b通过调节Wbp2表达以依赖酶活性的方式损害了全身葡萄糖平衡

Lianju Li1,2, Yaoyu Zou3, Chongrong Shen1,2

  • 1Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

Heliyon
|September 19, 2024
PubMed
概括

通过降低Wbp2蛋白水平,在肝脏中过度表达Dyrk1b会降低葡萄糖耐受性. 抑制Dyrk1b可以改善葡萄糖代谢,为代谢障碍揭示了一个新的治疗点.

关键词:
这就是Dyrk1bb.葡萄糖的恒常性是葡萄糖的恒常性.葡萄糖耐受性是一种耐受性.胰岛素耐药性 胰岛素耐药性是一种2 型糖尿病 2 型糖尿病这就是Wbp2的意思.

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