与无症状的韩国成年人结直肠腺瘤相关的鱼肉摄入量
Young Sun Kim1, Akinkunmi Paul Okekunle2,3, Sun Young Yang1
1Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Republic of Korea.
Frontiers in nutrition
|September 19, 2024
概括
较高的鱼类摄入量可能会降低韩国人患高风险结直肠腺瘤的风险. 这项研究没有发现肉类消费与腺瘤患病率之间的明显联系,但鱼类摄入量显示出一种保护性趋势,特别是在男性中.
科学领域:
- 胃肠病学 胃肠病学
- 营养流行病学 营养流行病学
- 在瘤学瘤学.
背景情况:
- 结肠直肠腺瘤是结肠直肠癌的前体.
- 识别饮食因素对于预防癌症至关重要.
- 亚洲人口的流行病学数据有限.
研究的目的:
- 调查鱼类和肉类摄入量与韩国人的结直肠腺瘤风险之间的关联.
- 探索潜在的饮食修改,以预防结直肠癌.
主要方法:
- 一项涉及536名腺瘤患者和1,122名对照者的病例控制研究.
- 参与者填写了一份食物频率问卷.
- 多变量逻辑回归分析了饮食和腺瘤状况之间的关系.
主要成果:
- 在总鱼类,肉类,红肉,肉或加工肉类摄入量和整体结直肠腺瘤患病率之间没有发现显著的关联.
- 较高的鱼类摄入量与高风险的结直肠腺瘤相反相关 (P趋势=0.04).
- 这种反向关联在男性中更为明显 (P为趋势=0.01).
结论:
- 高鱼类摄入量与韩国人口中高风险结直肠腺瘤的发病率降低有关.
- 饮食肉 (红肉,加工肉,肉) 摄入量与结直肠腺瘤风险没有明确的关联.
- 研究结果表明,鱼类消费可能在预防晚期结直肠腺瘤方面发挥作用,特别是在男性中.
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