视网膜神经纤维层缺陷和慢性病:凯卢安眼睛研究
Qian-Qian Wan1,2, Jin-Qiong Zhou1, Li-Jian Fang3
1Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
International journal of ophthalmology
|September 19, 2024
概括
视网膜神经纤维层缺陷 (RNFLDs) 与中国成年人的慢性病 (CKD) 严重程度有关. 眼底镜可以帮助检测CKD,建议RNFLD作为这种系统性疾病的眼睛指标.
科学领域:
- 眼科医生 眼科 眼科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 是一个重要的公共卫生问题.
- 眼部表现可以作为系统性疾病的指标.
- 视网膜神经纤维层缺陷 (RNFLDs) 是潜在的,但尚未得到充分研究的,系统性疾病的生物标志物.
研究的目的:
- 为了确定RNFLD是否是中国成年人群中CKD的风险因素.
- 调查RNFLD与CKD严重程度之间的关联.
- 探索 fundoscopy 在识别系统性疾病指标,如 RNFLDs 的实用性.
主要方法:
- 一项以人口为基础的研究,Kailuan眼睛研究,包括14440名参与者.
- 参与者接受了全面的系统检查和视网膜成像.
- 使用彩色底部照片诊断RNFLD.
主要成果:
- 在12507名具有完整数据的参与者中,RNFLD在5.0%的个体中被发现.
- RNFLD与CKD严重程度有显著的关联,在3,4和5阶段的几率比率上升.
- 在18.34%的参与者中存在CKD,其存在与RNFLD有显著的相关性.
结论:
- 结核病和高血压被确定为RNFLD最强的危险因素.
- RNFLD可以作为一种标志着CKD的眼部特征.
- 建议在CKD患者中进行RNFLD评估的基底镜检查,以早期检测全身疾病.
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