案例报告:与Mycoplasma pneumoniae相关的急性胰腺炎
Hong Sun1, Wei-Qun Wang1, Long Lin1
1Department of Pediatrics, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, Zhejiang, China.
Frontiers in pediatrics
|September 19, 2024
概括
在儿童中,Mycoplasma pneumoniae感染可能导致急性胰腺炎. 这一案例凸显了在患有M.肺炎和腹部疼痛的儿童中考虑胰腺炎的必要性.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- 菌性肺炎是儿童社区获得性肺炎的常见原因.
- 肺炎感染的肺外并发症是多样化的,急性胰腺炎是一种罕见但已报告的表现.
- 有记录的与M. pneumoniae相关的急性胰腺炎病例不到30例.
研究的目的:
- 在儿童中报告急性胰腺炎的病例,这是由于Mycoplasma pneumoniae感染的次要原因.
- 强调在M. pneumoniae感染儿童出现腹部疼痛的差异诊断中考虑急性胰腺炎的重要性.
主要方法:
- 一个临床病例报告,一个4岁的女孩患有M. pneumoniae感染和随后急性胰腺炎的症状.
- 诊断工作包括对M. pneumoniaeIgM的血清测试,胰腺炎的生化标志物 (脂酶,氨酶) 和腹部CT.
- 对血清炎症性细胞因子水平 (IL-2,IL-6,IL-17A,TNF,IFN-玛) 的分析.
主要成果:
- 患者出现了发烧,咳,并确认了M. pneumoniaeIgM抗体.
- 腹部疼痛,脂酶和粉酶水平升高,以及CT上扩散的胰腺炎表明急性胰腺炎.
- 观察到几种炎症性细胞因子的水平升高.
- 排除了胰腺炎的其他原因,确定M. pneumoniae是致病原体.
结论:
- 在儿童中,Mycoplasma pneumoniae感染可能导致急性胰腺炎.
- 在患有M. pneumoniae感染和腹部疼痛的儿科患者的差异诊断中,应考虑急性胰腺炎.
- 炎症性细胞因子可能在M. pneumoniae相关胰腺炎的发病过程中发挥作用.
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