在外周注射类固醇注射后多久可以预测患者的反应?
Byron J Schneider1, Valentine U Chukwuma1, Blake M Fechtel1
1Department of Physical Medicine and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
Interventional pain medicine
|September 19, 2024
概括
外周注射类固醇注射 (ESI) 提供根性疼痛缓解,许多患者在几天内经历了显著的疼痛减轻. 第4天的早期积极反应预测了长期的成功,强调了ESI后及时疼痛评估的重要性.
科学领域:
- 疼痛管理 疼痛管理
- 脊柱干预手术 脊柱干预手术
- 康复医学 康复医学 康复医学
背景情况:
- 外周注射类固醇注射 (ESI) 是治疗根性疼痛的常见方法.
- 之前的研究没有详细说明患者对ESI反应的具体时间表.
研究的目的:
- 描述ESI后患者经历的缓解疼痛的时间模式.
主要方法:
- 在一个学术脊柱中心连续接受ESI的134名患者的前性研究.
- 在注射后的21天内,患者每3天进行一次评估,使用数值疼痛得分和百分比疼痛缓解.
- 分析包括基于早期反应预测3周结果的概率比率.
主要成果:
- 47.2%的患者报告说,在3周内至少减少了50%的疼痛.
- 在响应者中,72.5%的人在第一天获得了50%以上的缓解,而其他人则报告了4日,13日,16日或22日的发作.
- 第4天的患者反应预测了3周的结果,正负概率率表明了预测值.
结论:
- 这项研究为患者对ESI反应提供了第一个详细的时间表.
- 患者在ESI后第4天的疼痛反应是他们3周结果的重要预测因素.
- 在第7天或第10天持续缓解疼痛进一步增加了积极的3周结果的可能性.
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