在夏威夷和太平洋中部地区追踪猪肉病的血清分子趋势
Thi Hai Au La1, Ian A McMillan1, Prashant Dahal1
1Pathogen Analysis and Translational Health Group, School of Life Sciences, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Frontiers in public health
|September 19, 2024
概括
在夏威夷,野猪的感染率很高,因此菌病是夏威夷的一个显著的动物感染风险. 这项研究绘制了高风险地区的地图,并分析了Brucella suis菌株,揭示了与美国菌株的联系.
科学领域:
- 兽医传染病 兽医传染病
- 动物传播疾病流行病学
- 分子流行病学分子流行病学
背景情况:
- 乳病是一种由布鲁塞拉菌种引起的动物传播疾病,对哺乳动物和人类构成风险.
- 夏威夷的野猪是已知的布鲁塞拉病毒携带者,增加了向其他动物和人类传播的风险.
研究的目的:
- 评估夏威夷各地野猪中兽病的流行率和空间分布.
- 为了在夏威夷进行Brucella suis菌株的分子流行病学分析.
主要方法:
- 在15年的时间里,分析了来自5个岛屿的3274个野猪血清样本.
- 血清阳性数据的空间分析和流域采样.
- MLVA和全基因组SNP分析用于B的分子特征. 瑞士. 瑞士.
主要成果:
- 野生猪在全州的血清阳性率是美国大陆的三倍.
- 在毛伊,奥阿胡和夏威夷岛上观察到最高的阳性率,并确定了特定的热点.
- 在夏威夷,B. 苏伊士菌株在遗传学上最接近美国菌株,属于biovar 1遗传组.
结论:
- 这项研究确定了在夏威夷的野猪中具有高血清阳性的关键岛屿和流域,强调了动物传播风险.
- 基因组分析提供了对该地区兽病史和本地流行病学的见解.
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