在一项大型流行病学研究ESSE-RF中,睡眠的预测因素
Mikhail Bochkarev1, Lyudmila Korostovtseva1, Oxana Rotar1
1Almazov National Medical Research Centre, Saint Petersburg, Russia.
Frontiers in neurology
|September 19, 2024
概括
过度白天嗜睡 (EDS) 影响近6%的俄罗斯成年人,与睡眠问题,药物和健康状况有关. 了解这些预测因素是改善睡眠健康管理的关键.
科学领域:
- 公共卫生 公共卫生
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 过度白天嗜睡 (EDS) 是一种普遍的疾病,对公共健康有重大影响.
- 俄罗斯地区心血管疾病流行病学 (ESSE-RF) 研究提供了一个强大的数据集,用于调查大量人群中的睡眠障碍.
研究的目的:
- 确定俄罗斯成年人口中过度白天嗜睡的关键预测因素.
- 探索睡眠投诉,生活方式因素,医疗状况和EDS之间的联系.
主要方法:
- 来自ESSE-RF队列研究 (2012-2013) 的13,255名25-64岁参与者的数据分析.
- 用于睡眠投诉和药物使用的采访,以及全面的社会,人口,人体,生活方式和实验室数据.
- 采用多变量回归分析来确定频繁嗜睡 (≥3次/周) 的显著预测因素.
主要成果:
- 5.8%的受访者报告经常性嗜睡;10.8%的受访者报告偶尔性嗜睡.
- 重要预测因素包括睡眠投诉 (失眠,睡眠呼吸暂停,打),经常使用睡眠药物,年龄较大,女性性别,高等教育和退休状态.
- 另外发现的预测因素包括异常焦虑,低高脂胆固醇,高盐摄入量以及心律不整,高血压,心肌梗塞,其他心脏病和病等疾病.
结论:
- 该研究证实,俄罗斯的EDS患病率很高,与全球模式一致.
- 人口,睡眠,心理和医疗因素的复杂相互作用导致EDS.
- 研究结果强调需要个性化方法来管理EDS并改善睡眠健康.
相关概念视频
Insufficient Sleep and Sleep Deprivation
134
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
134
Correlations
32.7K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
32.7K
Sleep-Wake Cycles
1.2K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K
Sedatives and Hypnotics Drugs: Miscellaneous Agents
157
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
157


