肺癌支气管镜检查期间快速现场评估的诊断性能:一个全面的元分析
Cheng-Chieh Chen1, Shou-Cheng Lu2, Yu-Kang Chang3,4
1Department of Pathology, Saint Paul's Hospital, Taoyuan, Taiwan.
Cancer cytopathology
|September 19, 2024
概括
支气管镜检查期间的快速现场评估 (ROSE) 显示了诊断肺癌的高准确性. 这种方法可以提高低剂量计算机断层扫描 (LDCT) 查的患者的检测率,并通过内支气管超声波引导的横支气管针吸收 (EBUS-TBNA) 提高节点分期的准确性.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 肺癌是全球癌症死亡的主要原因之一.
- 低剂量计算机断层扫描 (LDCT) 查可以降低高风险个体的肺癌死亡率.
- 支气管检查与内支气管超声导向跨支气管针吸收 (EBUS-TBNA) 用于肺癌诊断和分期.
研究的目的:
- 在肺癌支气管镜检查期间评估快速现场评估 (ROSE) 的诊断准确性.
- 评估ROSE与LDCT查和EBUS-TBNA联合用于肺癌分期的实用性.
主要方法:
- 对来自PubMed,Embase和Cochrane图书馆的研究进行了元分析.
- 包括的研究评估了ROSE在支气管镜检查期间肺癌的诊断准确性.
- 一个双变的随机效应模型被用于元分析.
主要成果:
- 分析包括32项研究,包括8243个肺病变,得出91.8%的综合灵敏度和94.9%的特异性.
- 对接受计算机断层扫描的患者的亚组分析显示,聚合灵敏度为93.8%,特异性为96%.
- 对于使用EBUS-TBNA的节点分期,ROSE显示了90.1%的聚合灵敏度和96.9%的特异性.
结论:
- 快速现场评估 (ROSE) 显示了高灵敏度和特异性,用于诊断支气管镜检查期间的肺癌.
- 在接受LDCT查的患者中,ROSE有效检测肺癌.
- 在接受EBUS-TBNA的肺癌患者中,ROSE为结节分期提供了高特异性.
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