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Updated: Jun 12, 2025

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一种基于甲基硫胺的NLRP3炎症酶小分子抑制剂的功能性表征

Savannah Biby1, Prasenjit Mondal2, Yiming Xu1

  • 1Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298, United States.

ACS chemical neuroscience
|September 19, 2024
PubMed
概括

YM-I-26是一种新的小分子,可以选择性地抑制NLRP3炎症酶. 这种化合物表现出抗炎作用并改善细胞,支持其作为NLRP3相关疾病治疗的潜力.

关键词:
含有3 (NLRP3) 的NOD类受体家族的pyrin域.结合性相互作用 结合性相互作用抑制剂抑制剂的作用微质细胞中的微质细胞神经炎症是一种神经炎症.发酵细胞的形成 发酵细胞的形成

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