在东非利用土著植物来治疗乳腺癌:概述
Esther Ugo Alum1,2, Tabussam Tufail3,4, Daniel Ejim Uti1,5
1Department of Research and Publications, Kampala International University, Kampala, P. O. Box 20000, Uganda.
Anti-cancer agents in medicinal chemistry
|September 19, 2024
概括
东非药用植物在乳腺癌治疗方面表现有前途,提供具有抗癌功能的天然化合物. 进一步的研究可能会导致更有效和可持续的疗法,改善患者的治疗结果.
科学领域:
- 民族植物学和植物化学.
- 瘤学和药理学方面的研究.
背景情况:
- 乳腺癌对全球健康造成重大负担,传统治疗面临诸如副作用和耐药性等挑战.
- 现有的乳腺癌治疗方法,包括化疗和放射治疗,在疗效和患者耐受性方面存在局限性.
研究的目的:
- 审查来自东非的药用植物在治疗乳腺癌方面的潜力.
- 为了确定这些传统疗法的生物活性化合物和抗癌性质.
主要方法:
- 对2003年至2023年间发表的研究进行了文献搜索.
- 搜索的数据库包括谷歌学者,PubMed,Scopus,科学网和科学直接.
- 关键词集中在东非 (肯尼亚,埃塞俄比亚,乌干达,坦桑尼亚,卢旺达) 的乳腺癌和药用植物.
主要成果:
- 一些东非药用植物,包括*Cymbopogon citratus*,*Prunus africana*,*Withania somnifera*和*Curcuma longa*,含有具有显著抗癌性能的化合物.
- 这些天然化合物在减少癌症的攻击性,抑制癌症增殖和调节癌症途径方面表现出有效性.
- 研究越来越多地专注于这些天然和食化合物,用于新的乳腺癌治疗策略.
结论:
- 东非药用植物提供了一个有前途的补充性乳腺癌治疗途径,因为它们的负担能力和文化相关性.
- 对这些植物及其生物活性成分的进一步研究可能会彻底改变乳腺癌的治疗方法并提高生存率.
- 保护和整合传统的治疗实践对于利用东非植物在瘤学中的全部潜力至关重要.
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