一个系统的审查最近在尿路感染干预和治疗技术的进展
M S Alam1, M J Anwar, M S Akhtar
1Department of Pharmacy Practice, College of Pharmacy, National University of Science and Technology, Bosher-Muscat, Oman. m.anwar@qu.edu.sa.
European review for medical and pharmacological sciences
|September 19, 2024
概括
由于抗菌素耐药性,尿路感染 (UTI) 的治疗越来越困难. 新的疗法,如曼诺,皮利和疫苗正在出现,以及对新策略的调查. 这一综述强调了尿路感染治疗的进展.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 尿路感染 (UTI) 在全球范围内很常见,影响所有人口.
- 增加尿病原体的抗菌素耐药性是一个重大的临床挑战.
- 由于其高患病率和潜在并发症,有效治疗尿路感染至关重要.
研究的目的:
- 审查当前治疗进展和治疗尿路感染的干预措施.
- 提供针对尿路感染中抗菌素耐药性的新兴治疗方法的概述.
- 要突出最近在UTI管理策略的发展.
主要方法:
- 在MEDLINE,PubMed和ClinicalTrials.gov.gov.的综合文献搜索中进行了全面的文献搜索.
- 提取有关尿路感染治疗策略和临床试验的相关数据.
- 综合有关尿路感染新型和试验性治疗方法的信息.
主要成果:
- 抗微生物耐药性泌尿病原菌菌株,特别是大肠杆菌 (Escherichia coli) 的流行率越来越高.
- 开发有针对性的疗法,包括曼诺杀剂,皮利杀剂和疫苗.
- 研究替代策略,如离子泳,水凝涂层导管和抗菌膜疗法.
- 2014-2019年间临床试验活动增加表明对各种尿路感染治疗的兴趣日益增加.
结论:
- 抗菌素耐药性需要新的治疗方法来治疗尿路感染.
- 有针对性的药物 (曼诺赛德,皮利赛德) 和疫苗对抗耐药性尿路病原体具有前景.
- 对水凝涂层导管和抗菌膜治疗等替代方法的持续研究至关重要.
- 有效的尿路感染管理需要一个多方面的策略,特别是在女性.
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