英国前列腺癌的发病率,患病率和存活率
Eng Hooi Tan1, Edward Burn1, Nicola L Barclay1
1Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
JAMA network open
|September 19, 2024
概括
在2000年至2021年期间,前列腺癌的发病率和患病率在英国随年龄增加. 高生存率凸显了严重的疾病负担,特别是在老龄化人口中.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 前列腺癌护理管理依赖于发生率,流行率和存活率数据.
- 了解这些指标对于资源配置和医疗保健规划至关重要.
研究的目的:
- 确定从2000年到2021年在英国的前列腺癌发病率,流行率和生存率.
- 分析按年龄和日历年分层的趋势.
主要方法:
- 一项基于人口的队列研究,利用来自临床实践研究数据链接 (CPRD) GOLD和Aurum的英国初级保健数据.
- 纳入标准:18岁以上的男性患者,有至少一年的病史.
- 对发病率 (IR),周期流行率 (PP) 和1年,5年,10年生存率的分析.
主要成果:
- 在2000年至2021年期间,前列腺癌发病率从每10万人年增加了109到159,在2004年和2018年达到峰值.
- 在研究期间,月经期的患病率增加了三倍以上,从0.4%上升到1.4%.
- 平均存活时间约为11年,1年,5年和10年的生存率分别为93-94%,72-73%和53-54%,随着时间的推移呈现出改善.
结论:
- 发病率和流行率随着年龄的增长而上升,这表明老年人群的疾病负担很大.
- 患病率的增加需要医疗保健系统的适应,以管理越来越多的前列腺癌幸存者.
- 高生存率凸显了老龄化人口中幸存者护理的重要性.
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