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Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

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Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
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CNS Stimulants: Psychedelic Agents01:22

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Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
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Altered States of Awareness01:06

Altered States of Awareness

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Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
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Ethics in Research01:56

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Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
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Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
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在十字路口的迷幻研究

Stacey B Armstrong1, Alan K Davis2

  • 1Stacey B. Armstrong is a senior researcher and associate director at the Center for Psychedelic Drug Research and Education, College of Social Work, The Ohio State University, Columbus, OH, USA.

Science (New York, N.Y.)
|September 19, 2024
PubMed
概括
此摘要是机器生成的。

心理辅助疗法 (PAT) 对心理健康有很大的影响, 但安全性和有效性仍存在问题. 解决研究挑战对于开发基于证据的治疗方法至关重要.

科学领域:

  • 神经科学
  • 精神病学
  • 临床心理学

背景情况:

  • 全球每8人中就有1人患有精神疾病,
  • 心理学辅助治疗 (PAT) 结合心理学与心理治疗,正在临床试验中进行研究.
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