在泌尿外科手术前,对细菌性尿症进行适当的抗菌素处方:改善的空间
Thibaud Garnier1, Philippe Lesprit2, Clément Sarrazin1
1Department of Urology, CHU Grenoble Alpes, Grenoble, France.
The French journal of urology
|September 19, 2024
概括
对于阳性尿液培养的手术前抗生素处方往往与传染病专家的建议不同,全科医生会开更长时间的处方. 优化抗生素使用对于打击抗菌素耐药性至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 抗微生物药物管理委员会
背景情况:
- 阳性手术前尿液培养需要抗生素治疗,以确保尿路灭菌.
- 抗生素选择对于降低选择性压力和抗菌素耐药性至关重要.
- 泌尿科医生和全科医生 (GP) 目前的处方做法需要评估.
研究的目的:
- 评估手术前阳性尿液培养的抗生素处方模式.
- 为了比较泌尿科医生和GP的抗生素选择与传染病专家的建议.
- 确定在抗生素管理方面需要改进的领域.
主要方法:
- 对196种手术前尿液培养的回顾性审查 (2022年11月 - 2023年7月).
- 收集关于抗生素类别,持续时间和处方者的数据.
- 由传染病专家进行盲目审查,以确定理想的抗生素治疗.
主要成果:
- 20% (40/196) 的处方不同于专家建议,主要是使用广谱抗生素.
- 50%的不合格处方超过了推的48小时持续时间.
- 一般医生处方的治疗持续时间明显较长 (4.84天对2.99天,P<0.001).
结论:
- 泌尿科医生的抗生素处方需要优化以最大限度地减少生态影响.
- 将处方委托给没有专业培训的全科医生,导致不合理的治疗延期.
- 需要改善抗生素管理,以减少耐药性和优化患者的治疗结果.
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