患有心房的患者的血管疾病和缺血性中风:时间趋势和与年龄相关的差异
Konsta Teppo1, Elin Karlsson2, Tuomas Kiviniemi1
1Heart Centre, Turku University Hospital and University of Turku, Turku, Finland.
Atherosclerosis
|September 19, 2024
概括
血管疾病增加了心房患者的缺血性中风风险,特别是65岁以下的患者. 这种关联随着时间的推移而保持稳定,老年AF患者的患病率上升.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 是一种常见的心律失常,与缺血性中风 (IS) 的风险增加有关.
- 血管疾病是已知的IS风险因素,但它们的时间趋势和AF患者的特定年龄关联需要检查.
研究的目的:
- 调查AF患者血管疾病患病率的时间趋势.
- 评估AF患者血管疾病患病率的年龄相关差异及其与IS风险的关联.
主要方法:
- 使用了FinACAF注册 (2007-2018) 包括所有芬兰AF患者.
- 使用波桑回归计算IS的发生率比率 (IRR).
- 评估了血管疾病,年龄和日历年之间的相互作用.
主要成果:
- 在AF患者中血管疾病的患病率从2007年至2018年增加,特别是在75岁以上的患者中.
- 血管疾病独立地与65岁以下的AF患者中较高的IS发病率有关 (IRR1.35).
- 周围动脉疾病是老年AF患者中与IS相关的唯一血管疾病;没有观察到时间相互作用.
结论:
- 血管疾病和AF患者的IS之间的联系随着时间的推移一直保持一致.
- 血管疾病在年轻的AF患者 (<65岁) 中具有显著更高的IS风险.
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