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为未来优化前列腺活检和成像 - - 一项综述
Kimberley Chan1, Drkhairul Asri Mohammad Ghani2, Jeremy Teoh3
1Department of Urology, Hertfordshire and Bedfordshire Urological Cancer Center, Lister Hospital, Stevenage.
Urologic oncology
|September 19, 2024
概括
通过直肠超声波引导的前列腺活检 (TRUS-Bx) 错过了显著的癌症和毒症的风险. 跨膜前列腺活检 (TP-Bx) 和像PSMA-PET这样的先进成像技术可以改善前列腺癌的诊断.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 跨直肠超声导向前列腺活检 (TRUS-Bx) 是诊断前列腺癌的常规方法.
- TRUS-Bx具有局限性,包括缺失高达18%的临床显著前列腺癌 (csPCa) 和2.4%的败血症风险.
- 跨关前列腺活检 (TP-Bx) 已成为一种替代技术.
研究的目的:
- 审查目前的前列腺活检技术.
- 为了提供有关先进前列腺成像模式的最新信息.
- 突出前列腺特异性膜抗原-质子发射断层扫描 (PSMA-PET) 在前列腺癌检测中的作用.
主要方法:
- 关于前列腺活检和成像的现有文献的叙事综述.
- 讨论从TRUS-Bx到TP-Bx的演变.
- 专注于多参数MRI (mpMRI) 和PSMA-PET的诊断能力.
主要成果:
- TRUS-Bx可以错过临床上显著的前列腺癌.
- mpMRI有助于可视化可疑区域,可能避免不必要的活检.
- PSMA-PET对初级诊断和检测转移性病变的准确性比传统成像更高,显示出很大的前景.
结论:
- TP-Bx为TRUS-Bx提供了一个替代方案,解决了其一些局限性.
- 先进的成像,特别是PSMA-PET,正在彻底改变前列腺癌诊断.
- 这些进展旨在提高前列腺癌检测和管理的准确性和效率.
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