灵长类高级结合体因果地参与抽象的高阶认知
Barbara Peysakhovich1, Ou Zhu1, Stephanie M Tetrick1
1Department of Neurobiology, The University of Chicago, Chicago, IL, USA.
Nature neuroscience
|September 19, 2024
概括
上层结肠,一个中脑区域,在像抽象视觉分类这样的高阶认知中发挥着关键作用. 这一发现挑战了关于它超出空间定向之外的功能之前的假设.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 灵长类的神经生物学
背景情况:
- 上 (SC) 传统上与空间定位有关,包括眼睛运动和注意力.
- 它在高阶认知功能中的潜在作用在很大程度上仍未被探索.
研究的目的:
- 为了研究上层结体在抽象视觉分类中的作用,独立于空间定向函数.
- 为了比较SC中类别的神经编码与后壁皮质皮质 (PPC).
主要方法:
- rhesus 被训练在一个抽象的视觉分类任务.
- 在SC和PPC中记录和比较神经活动.
- 评估了SC失活对分类性能的影响.
主要成果:
- SC展示了对已学习的视觉类别的强大编码.
- 与PPC相比,SC中的类别编码更强大,并以类似的延迟出现.
- 关闭SC显著影响了抽象类别的决策.
结论:
- 灵长类动物的上层结膜介导抽象的,高阶的认知过程.
- 这些认知功能以前主要归因于新皮质.
- 委员会作用不仅仅是空间定向,还涉及到复杂的决策.
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