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Updated: Jun 12, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
00:06

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Published on: September 12, 2019

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肝细胞癌特异性表观遗传检查点双向调节CD4+T细胞的抗瘤免疫力

Shuai Wang1, Lijun Meng2, Nan Xu3

  • 1Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou First People's Hospital, Hangzhou, 310006, China. wmmkao2@163.com.

Cellular & molecular immunology
|September 19, 2024
PubMed
概括

这项研究揭示了MATR3作为肝细胞癌 (HCC) 中CD4+T细胞功能的关键调节者. 过度表达的MATR3通过促进T细胞耗尽而损害抗瘤免疫力,为HCC提供了新的治疗点.

关键词:
在 ARID1A 中.消耗 耗尽 已经 耗尽 已经 耗尽这就是 MATR3R3 的意义.托克斯 (Tox) 是一种毒素.这就是为什么Tconvv.

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