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正静性血压表型2型糖尿病中患病率
Ana Raquel Whitaker1, Joaquim Barreto1, Wilson Nadruz2
1Faculty of Medical Sciences, Laboratory of Atherosclerosis and Vascular Biology, University of Campinas, Sao Paulo, Brazil.
正静性低血压和高血压在2型糖尿病患者中很常见. 晚年增加了正静性低血压的风险,而坐着的血压是这两种情况的关键因素.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 临床研究 临床研究
背景情况:
- 正静性低血压 (OHypo) 和正静性高血压 (OHyper) 是已知的心血管事件风险的早期指标.
- 关于OHypo和OHyper的患病率和风险因素的数据有限,特别是在2型糖尿病 (T2D) 患者中.
研究的目的:
- 在2型糖尿病患者中调查静止性低血压和静止性高血压的患病率和相关风险因素.
- 在T2D人口中确定这些疾病的人口和临床预测因素.
主要方法:
- 在巴西糖尿病研究中进行了一项观察性,横截面研究. 巴西糖尿病研究.
- OHypo被定义为站立时血压显著下降 (静脉缩≥20mmHg或静脉缩≥10mmHg).
- OHyper被定义为静脉压在站立时 (≥20mmHg) 或持续高血压时显著增加的静脉压.
主要成果:
- 这项研究包括900名T2D患者 (平均年龄57岁,57%是男性).
- OHypo (108名患者) 的患病率为12%,OHyper (83名患者) 的患病率为9%.
- 增加的年龄与更高的OHypo几率 (每年3.7%) 有关. 更高的静坐静脉血压,静脉血压和平均动脉压也增加了OHypo的几率.
结论:
- 在T2D患者中,OHypo和OHyper是普遍存在的.
- 高龄是OHy.的重要危险因素.
- 坐着血压是T2D中OHypo和OHyper的独立风险因素.
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