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Updated: Jun 12, 2025

Quantification of Coenzyme A in Cells and Tissues
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CoA合成酶在神经发育和神经退行中发挥着关键作用

Chiara Cavestro1, Marco D'Amato1, Maria Nicol Colombo1

  • 1Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Frontiers in cellular neuroscience
|September 20, 2024
PubMed
概括

由于COASY基因变异导致的协酶A (CoA) 合成缺陷会导致神经退行症和脑小细胞缺血症. 一种新的小鼠模型显示,CoA缺乏会影响大脑发育,导致星细胞异常和神经炎症.

关键词:
与COASY蛋白相关的神经退行症.在 CoA 合成酶.动物模型动物模型神经退行症的神经退行症神经发育的神经发育第12类点脑小贝低成形症

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