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Updated: May 1, 2026

Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons
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在暴露于沙林替代神经毒剂后,人类iPSC衍生的神经网络活动的双相反应

Chandrakumar Bogguri1, Vivek Kurien George2, Beheshta Amiri1

  • 1Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA, United States.

Frontiers in cellular neuroscience
|September 20, 2024
PubMed
概括

有机神经毒剂 (OPNA) 暴露会影响神经网络的通信,其影响因度而异. 一个与人类相关的多电极阵列 (MEA) 系统监测了这些变化,显示在去除剂后恢复,但在高剂量下持续作用.

关键词:
急性暴露的急性暴露.人类诱导的多能干细胞干细胞.人类的神经元活动.微生理系统的微生理系统多电极阵列多电极阵列.这是一种神经毒剂.有机酸盐是一种有机酸

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