作为疏忽训练的附加剂的阿尔法横交替电流刺激:一个随机试验
Marij Middag-van Spanje1,2, Tanja C W Nijboer3,4, Jan Schepers5
1Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands.
Brain communications
|September 20, 2024
概括
多会话横交替电流刺激与视觉扫描培训相结合,改善了视觉搜索和检测在视觉空间疏忽的慢性中风患者,为中风恢复提供了有前途的补充治疗.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 认知科学 认知科学
背景情况:
- 视觉空间疏忽是单边中风的常见后果,损害了日常功能.
- 需要有效治疗慢性视觉空间疏忽,以改善患者的治疗结果.
- 非侵入性脑刺激,如间交流电刺激 (tACS),是潜在的中风恢复补充疗法.
研究的目的:
- 评估多会程α频 tACS 与视觉扫描训练 (VST) 结合在患有视觉空间疏忽的慢性中风患者的附加效应.
- 为了比较活跃的alpha-tACS加VST与假的tACS加VST.
主要方法:
- 这是一项双盲随机对照试验,涉及22名慢性视觉空间疏忽患者.
- 参与者在6周内接受了18次40分钟的活跃或假的alpha-tACS与VST相结合.
- 评估包括在多个时间点进行视觉搜索 (明星取消),视觉检测,线路分割和日常生活任务.
主要成果:
- 与假装组相比,活跃的α-tACS组在被忽视的方面显著改善了视觉搜索和视觉检测性能.
- 在线切割任务或日常生活措施上没有观察到显著的影响.
- 在大多数结果指标中观察到时间效应,这表明研究期间的整体改善.
结论:
- 与VST结合的多会话alpha-tACS可能比单独使用VST更有效治疗慢性视觉空间疏忽.
- 这种综合方法为增强认知康复和改善中风后的生活质量提供了一种新的策略,即使是在初始受伤后很长时间.
- 这些发现支持tACS作为中风恢复干预的有价值工具.
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