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固体脂质纳米颗粒在药物输送中的制备,性能和应用方面的最新进展

Ujjwal Kumar Biswas¹, Anindya Bose¹, Ankita Parmanik¹

¹School of Pharmaceutical Science (SPS), Siksha O Anusandhan (SOA) University, K.8, Kalinga Nagar, Ghatkia, Bhubaneswar- 751003, Odisha, India.

Pharmaceutical nanotechnology

|September 20, 2024

概括

固体脂质纳米颗粒 (SLN) 提供生物相容和生物降解的药物输送解决方案. 本综述详细介绍了SLN制剂,特征和在制药配方中的应用.

科学领域:

制药纳米技术制药纳米技术
材料科学材料科学材料科学

背景情况:

固体脂质纳米颗粒 (SLN) 是药品中广泛使用的纳米载体.
它们的生物相容性和生物降解性推动了它们在药物输送中的应用超过30年.

研究的目的:

审查SLN制备技术和物理化学性质.
讨论SLN对制药药物递送系统的优势.
探索SLN的成分,药物应用以及未来的前景.

主要方法:

对各种SLN制备方法的审查 (例如,均化,基于微乳液).
讨论关键的物理化学特征 (药物加载,释放,颗粒大小,稳定性等). ) 的情况.
分析SLN配方成分和药物输送结果.

主要成果:

SLN 具有有利的特性,如控制药物释放和增强细胞吸收.
不同的制备方法可以产生具有可调节特性的SLN.
在各种药物输送途径中,SLN已经证明了其有效性.

结论:

SLNs是药物药物输送的多功能和首选的纳米载体.
了解SLN的特性和配方对于成功开发药物至关重要.
对于未来的制药创新,SLN具有显著的前景,包括监管和专利方面的考虑.

关键词:

固体脂质纳米颗粒固体脂质纳米颗粒生物成像 - 生物成像基因传递基因传递基因传递纳米技术是纳米技术.表面活性剂是一种表面活性剂.目标化方法的目标化方法.

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