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Murine Kidney Transplant Technique
Published on: October 20, 2015
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脏移植中的手术内平均动脉压和术后延迟移植功能:评估三种常用的值
Chinnarat Pongpruksa1,2, Nutchanok Khampitak3, Drew Chang1
1Department of Anesthesiology and Perioperative Medicine, Ronald Reagan UCLA, Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Clinical transplantation
|September 20, 2024
概括
在移植 (KT) 期间保持适当的平均动脉压 (MAP) 是至关重要的. 长时间低于常见MAP值 (≤75,80,85 mmHg) 的时间与成年KT接受者延迟移植功能 (DGF) 有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 临界护理医学 临界护理医学
背景情况:
- 延迟移植功能 (DGF) 是移植 (KT) 后的常见并发症,影响长期结果.
- 在KT期间最佳的血液动力学管理仍未完全定义.
- 本研究研究了特定平均动脉压 (MAP) 门和DGF之间的关联.
研究的目的:
- 评估三种常见的MAP值 (≤75,80和85 mmHg) 与成年KT患者DGF发病率之间的关系.
- 为了确定与DGF相关的低血压的临界持续时间.
主要方法:
- 从已故的成年捐赠者KT接受者的非识别数据的回顾性分析.
- DGF定义为在移植后7天内需要透析.
- 用于分析MAP值和持续时间作为DGF风险因素的多变量后勤回归.
主要成果:
- 包括2301名成年KT患者;46.3%的人经历过DGF.
- 在所有MAP值中观察到低血压的高患病率.
- 长时间在MAP值≤75 mmHg (≥6分钟),≤80 mmHg (≥23分钟) 和≤85 mmHg (≥37分钟) 以下的持续时间与DGF显著相关,即使在调整其他风险因素后也是如此.
结论:
- 在成年已故供体KT期间,经常和长时间暴露于常见MAP值 (≤75,80,85 mmHg) 与DGF风险增加有关.
- 这些发现强调了维持适当的手术内MAP的重要性,以改善KT的早期移植结果.
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