在儿科末期肝病的营养
Tejas S Desai1,2, Jessie M Hulst1,2,3, Robert Bandsma1,2,3
1The Hospital for Sick Children, Department of Pediatrics, Division of Gastroenterology, Hepatology & Nutrition.
Current opinion in clinical nutrition and metabolic care
|September 20, 2024
概括
患有末期肝病的儿童经常面临营养不良的挑战. 需要更多的研究来确定这些儿科患者的最佳营养策略.
科学领域:
- 儿科胃肠病学和肝病学
- 临床营养学 临床营养学
- 肝脏疾病研究 肝脏疾病研究
背景情况:
- 患有慢性和末期肝病 (ESLD) 的儿科患者极易患营养不良.
- 儿童的成长需求和慢性肝病的并发症加剧了营养挑战.
- 全球对慢性肝病营养不良的定义和方法缺乏标准化.
研究的目的:
- 审查最近关于儿科末期肝病营养状况和结果的研究.
- 突出当前的研究趋势,并识别文献中的差距.
主要方法:
- 对最近文献进行系统审查.
- 对研究的分析,重点是营养评估,肉症和移植结果.
- 儿科研究与该领域的成人研究的比较.
主要成果:
- 营养不良是儿科ESLD的一个重要问题,因生长需求和疾病因素而复杂化.
- 最近的研究强调了肉症和营养对移植结果的影响.
- 专门针对儿童的研究有限,落后于成人研究,前性或干预性试验很少.
结论:
- 在儿科ESLD中优化营养是具有挑战性的,但理解正在改善.
- 需要高质量的研究来确定ESLD儿童的最佳营养策略和干预措施.
- 未来的研究应该优先考虑对儿科患者群体的前性和干预性研究.
更多相关视频
相关概念视频
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
85
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
85
Liver Regeneration
3.2K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
3.2K
Enteral Nutrition I: Orogastric and Nasogastric Feeding
215
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
215
Liver Physiology
454
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
454
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
106
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
106
Overview of Protein Metabolism
823
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
823


