Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

161
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
161
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

447
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
447
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

83
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
83
Drug Dependence01:17

Drug Dependence

988
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
988
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

239
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
239
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance01:23

Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance

103
The elimination half-life and drug clearance of drugs following nonlinear kinetics can vary with dosage. The Michaelis-Menten parameters and drug concentration influence these factors. As the dose increases, the elimination half-life tends to lengthen, resulting in a reduction in clearance and a disproportionately larger area under the curve. The total clearance can be derived from the Michaelis-Menten equation for drugs following a one-compartment model.
A study on guinea pigs examined the...
103

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Digital divide in clinical and operational artificial intelligence adoption and implementation stages: US hospital diffusion patterns and AI deserts.

Journal of the American Medical Informatics Association : JAMIA·2026
Same author

Physical Activity, Sitting Time, and Sleep Among Postpartum Women During the COVID-19 Pandemic.

Birth (Berkeley, Calif.)·2026
Same author

Family-Based GWAS of Cognitive Endophenotypes Reveals Genetic Architecture of Memory and Executive Function in Alzheimer's Disease.

Current issues in molecular biology·2026
Same author

County-Level New HIV Diagnoses, Social Determinants of Health, and Residential Segregation by U.S. Region 2013 to 2023: A Longitudinal Analysis.

AIDS and behavior·2026
Same author

Economic Stability of Children, a Key Social Determinant of Health, in the United States: Differences by Rurality.

The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association·2026
Same author

Dyadic relationship between caregiving burden and perceived stress among people with HIV: moderated mediation analysis.

Psychology, health & medicine·2026

相关实验视频

Updated: Jun 12, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

85.8K

揭示周产期多物质使用的复杂性 披露模式在X上:混合方法研究研究

Dezhi Wu1, Hannah Shead2, Yang Ren3

  • 1Department of Integrated Information Technology, University of South Carolina, Columbia, SC, United States.

Journal of medical Internet research
|September 20, 2024
PubMed
概括

围产期多物质使用 (PPU) 关于X的讨论揭示了负面情绪和耻辱感. 酒精和药物组合很常见,突出了改善公共卫生支持和对孕妇的政策的需要.

关键词:
他们的推特是Twitter.围产期护理 围产期护理使用多种物质使用多种物质.怀孕护理 怀孕护理产前护理 产前护理情绪分析是一种情绪分析.社交媒体 社交媒体

更多相关视频

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

Published on: December 14, 2014

9.7K
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:25

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

180

相关实验视频

Last Updated: Jun 12, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

85.8K
Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

Published on: December 14, 2014

9.7K
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:25

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

180

科学领域:

  • 公共卫生 公共卫生
  • 社交媒体分析 社交媒体分析
  • 围产期护理 围产期护理

背景情况:

  • 孕妇使用多种物质 (PPU) 很普遍,但机制和背景尚不清楚.
  • 像X (以前的Twitter) 这样的社交媒体平台提供了大量关于公众论的有机数据.
  • 将传统的研究方法与自然语言处理 (NLP) 结合起来,可以获得宝贵的公共卫生见解.

研究的目的:

  • 分析2019年5月至2021年10月期间关于X的PPU讨论的趋势和情绪.
  • 识别与PPU相关的推特中的独特模式及其对围产期护理和政策的影响.

主要方法:

  • 使用X的API提取了600多万条推特,重点关注产前健康和物质使用关键词.
  • 过以寻找美国的推文,结果为4848个与PPU相关的推文,用于混合方法分析.
  • 采用了定量 (频率,趋势,情绪分析) 和定性 (对500条推文的主题内容分析) 的方法.

主要成果:

  • 与非PPU推特相比,PPU推特表现出更多的负面情绪 (51.36%).
  • 双重使用多种物质,特别是酒精和毒品是最常见的 (85.27%).
  • 关键主题包括生活方式,社会观念,法律问题和公共卫生问题驱动PPU.

结论:

  • X讨论突出了围绕围产期PPU的重大耻辱和法律影响.
  • 对PPU的公众情绪是混合的,观察到一种令人担忧的正常化趋势.
  • 研究结果为公共卫生从业者和政策制定者提供了关键的见解,以加强对PPU患者的支持.