2011年至2018年在中国马安山的癌症发生率和趋势:基于注册表的观察性研究
Qirong Qin1,2, Yuxin Min3,4, Yijing Xie3
1Chronic Disease Prevention and Health Management Department, Center for Disease Control and Prevention, Ma'anshan, China.
Cancer control : journal of the Moffitt Cancer Center
|September 20, 2024
概括
2011-2018年,中国马安山的癌症发病率仍然低于全国平均水平. 上部胃肠道癌症减少,而女性乳腺癌,结肠直肠癌和甲状腺癌增加,反映了国家趋势.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 中国面临着越来越多的癌症负担,对于像马安山这样的关键城市地区,发病率数据缺乏.
- 这项研究解决了在长江三角洲城市中部的马安山 (Ma'anshan) 当地癌症发病率数据的需求.
研究的目的:
- 为了确定2011年至2018年的Ma'anshan癌症发病率和趋势.
- 为该地区的癌症预防计划提供病因学的见解.
主要方法:
- 使用注册数据 (2011-2018) 计算癌症发病率和年龄标准化发病率 (ASIR).
- 使用joinpoint回归 (年平均百分比变化 - AAPC) 分析ASIR趋势.
- 通过年龄-时期-队列模型估计年龄,时期和队列效应.
主要成果:
- 记录了13,508名男性和9,558名女性癌症病例. 总体而言,ASIR保持稳定.
- 随着年龄的增长,癌症风险增加;没有观察到显著的月经期影响.
- 胃,食道和肝癌的发生率有所下降 (AAPC: -3.72%, -8.30%, -5.55%). 女性乳腺癌,结肠直肠癌和甲状腺癌的发病率上升 (AAPC:3.91%,3.23%,22.38%).
结论:
- 马安山的癌症发病率在2011-2018年期间低于中国全国平均水平.
- 上部胃肠道癌症的下降趋势与女性乳腺癌,结肠直肠癌和甲状腺癌的上升率形成对比.
- 这些发现与中国癌症谱的更广泛变化一致,需要进一步的病因学研究.
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