糖尿病患者足部并发症查的有效性 - - 一项系统性审查
Aleksandra Staniszewska1, Amy Jones2, Sarah Rudd2
1Translational Health Sciences, Bristol Medical School, University of Bristol, United Kingdom; North Bristol NHS Trust, Bristol, United Kingdom.
Journal of diabetes and its complications
|September 20, 2024
概括
基于人口的糖尿病脚部查可能会减少和截肢,但证据有限. 需要进一步的研究来证实它在预防下肢并发症和改善糖尿病患者的治疗结果方面的有效性.
科学领域:
- 糖尿病学 糖尿病学
- 血管外科 血管外科
- 公共卫生 公共卫生
背景情况:
- 糖尿病影响了四分之一的人,导致下肢截肢的风险增加了六倍.
- 脚是一种常见的并发症,需要有效的预防策略.
- 基于人口的足部查在预防糖尿病患者失去四肢的有效性仍然不确定.
研究的目的:
- 系统地审查基于人口的脚部查在减少糖尿病患者下肢并发症方面的有效性.
- 评估查对脚,截肢 (小和大截肢),住院和死亡率的影响.
主要方法:
- 随机和非随机对照试验和观察性研究的系统审查.
- 在MEDLINE,Embase,Emcare和CINAHL数据库中进行的搜索.
- 两个独立审查员进行了查,质量评估和数据提取.
主要成果:
- 在10,771项研究中,只有5项研究符合纳入标准.
- 一项研究显示,随着查,新的发生率减少了24%.
- 在三项研究中,重大截肢减少了17-96%,但住院率却相矛盾.
- 一项研究没有发现对轻微或重大截肢的影响,也没有评估所有原因的死亡率.
结论:
- 支持基于人口的足部查以预防与糖尿病相关的下肢并发症的证据基础目前在数量和质量上是有限的.
- 现有证据表明,查对关键临床结果的影响是可变的,这凸显了对更强大的研究的需要.
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